This patient case series has been developed with the assistance of Dr. Anna Gaya (Department of Hematology, Hospital Clinic of Barcelona, Barcelona, Spain). This program was supported by Alexion Pharmaceuticals.

The information presented is not intended as medical advice. Responsibility for patient care resides with the healthcare professional on the basis of their professional license, experience, and knowledge of the individual patient.

For full prescribing information, including indications, contraindications, warnings, precautions, and adverse events, please refer to the approved product labeling. Please note that products may have different product labeling according to geographical location. Within Europe, full prescribing information is available from the European Medicines Agency and Electronic Medicines Compendium:

www.ema.europa.eu/en/documents/product-information/ultomiris-epar-product-information_en.pdf

www.ema.europa.eu/en/documents/product-information/soliris-epar-product-information_en.pdf

www.medicines.org.uk/emc/product/11945

www.medicines.org.uk/emc/product/362

All characters and events depicted in this patient case simulation are entirely fictitious. Any similarity to actual events or persons, living or dead, is purely coincidental. This activity is intended for healthcare professionals. To proceed, please confirm that you are a healthcare professional.

Some drugs may not be available or licensed in your country/region. Please refer to your local medicines regulatory agency for more information.

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A 52-year-old man with AKI and malignant hypertension

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A 68-year-old woman with locally advanced cutaneous squamous cell carcinoma